Serum AFP levels after acute injury and during hepatocarcinogenesis
Wolf D. Kuhlmann
Laboratory Diagnostics & Cell Science, 56112 Lahnstein
Serum AFP levels in mice and rats after partial hepatectomy, CCl4 or GalN injury, respectively. Mean of 5 animals per day and study group. Abscissa: day 0 and during regeneration from day 1 to day 7. Ordinate: AFP µg/mL serum
Serum AFP levels in rats during early stages of liver carcinogenesis at high dose NNM feeding. Samples were taken at weekly intervals from day 8 through day 42. Abcissa: days of NNM feeding. Ordinate: AFP µg/mL serum
Serum AFP levels in rats measured over the time during hepatocarcinogenesis until carcinoma development. Animal No. 1 up to animal No. 7 were given high doses of NNM, while animal No. 8 up to No. 10 received low doses of NNM. Period of observation from 14 to 38 weeks. AFP levels and their rising rates differed due to the carcinogen burden and during carcinoma development. Abscissa: period of observation. Ordinate: AFP µg/mL serum
